Following the same formula as Breakfast with Tiffany, we have the story of Ros, who lost her two Moms to "a tragic accident involving foodstuffs." And while that sounds a bit like a joke, the story is actually a pretty serious one about learning to adjust to a new family, as Ros goes to live with her biological father (the sperm donor). There she must cope with her grief, some annoying kids at school, some even more annoying administrators, a few bad decisions, and an overly anxious new Dad. Dad, meanwhile, has to cope with Ros. Told through emails, journal entries, IMs, and random other media, the story unfolds through multiple viewpoints.
It's clever without getting saccharine and insightful without trying to be too cool. Again, it's hard to say what younger readers will think of it, but adults (and parents in particular) will enjoy the father's attempts to cope with his feelings and failures. So, maybe not a good YA book, but a good book all the same.